Vera Bradley founders Pat and Barb look back on the past 40 years as they venture into the metaverse

New York CNN — It all started with a knock on the door four decades ago. It was 1982 in Fort Wayne, Indiana, and Patricia R. Miller stopped by to introduce herself to new neighbor Barbara Bradley Baekgaard. “I happened to be a welcoming committee,” Miller told CNN Business with a laugh. “Barbara answered the … Read more

A cancer-fighting version of herpes shows promise in early human trials

An illustration of a herpes simplex virus. Illustration: Shutterstock (Shutterstock) Scientists may be able to turn a longtime bacterial enemy into a cancer-fighting ally, new research suggests this week. In preliminary data from a phase I trial, a genetically modified version of the herpes virus has shown promise in treating difficult-to-eradicate tumors, with one patient … Read more

Is exercise effective against constipation?

I recently presented a clinical scenario about one of my patients named Brenda in Constipation and Cramping: A Slam-Dunk Diagnosis? This 35-year-old woman came to me with symptoms that had already been going on for a year. I asked for readers’ comments on my management of Brenda. I appreciate the comments I have received on … Read more

Dating with an ostomy bag

When Harrison Kefford’s doctor first suggested an ostomy bag earlier this year, his dating life was the first thing that came to mind. “A lot of my fear and reasoning for why I initially didn’t want to go through with the ostomy was literally like, ‘How am I going to handle this when I have … Read more

Two factors for identifying men at greatest risk of death from prostate cancer

A family history of prostate cancer has long been one of the few universally accepted risk factors for the disease. New findings now show that risk stratification based on family history and inherited polygenic risk can identify men most at risk of dying from the disease before age 75 Men in the upper quartile of … Read more

AI tool may improve colorectal cancer recurrence prediction

Using artificial intelligence (AI), researchers have developed an algorithm that may help improve the prediction of colorectal cancer (CRC) recurrence. The QuantCRC algorithm can identify patients with CRC who may be able to skip chemotherapy given a low likelihood of relapse, and identify those patients at high risk of relapse who may benefit from more … Read more

How a pediatric hospital’s rare disease sequencing system unlocks the whole genome

That Children’s Mercy Kansas City The Research Institute announced this on Monday it builds what it calls the “most advanced genomic sequencing system in the world.” This claim refers to the work that Children’s Mercy does through its Genomic Answers for Kids (GA4K) program. The health system rolled out the program three years ago with … Read more

AI-guided tools pinpoint immune cell driver and protective genetic factor for esophageal cancer

Esophageal adenocarcinoma (EAC) is a type of cancer affecting the mucus-secreting glands of the lower esophagus -; the tube connecting the throat to the stomach. It is the most common form of esophageal cancer and often preceded by Barrett’s metaplasia (BE), a deleterious change in cells lining the esophagus. Although the cause of EAC remains … Read more

An unhealthy gut sets the stage for breast cancer to spread, research shows

Newsworthy – An unhealthy gut triggers changes in normal breast tissue that help breast cancer spread to other parts of the body, new research from the UVA Cancer Center reveals. The gut microbiome – the collection of microbes that naturally live inside us – can be disrupted by poor diet, long-term use of antibiotics, obesity … Read more